Researchers Optimistic After Man Cured of HIV in Experimental Trial
Science| | By Margo Gothelf
“We are exploring the real possibility of curing HIV,” Mark Samuels, a managing director of the National Institute for Health Research Office for Clinical Research Infrastructure explained to The Times. “This is a huge challenge and it’s still early days but the progress has been remarkable.” Current treatments cannot treat dormant T-cells, allowing them to reproduce the virus. “Currently, antiretroviral therapies can target active T-cells which are infected with HIV but they cannot treat dormant T-cells,” shared Gizmodo. However, this new experimental treatment targets the dormant cells making it a real game changer. “This therapy is specifically designed to clear the body of all HIV viruses, including dormant ones,” Professor Sarah Fidler, a consultant physician at Imperial College London, told The Times. The treatment, which works in two different stages, starts with a vaccine that recognizes HIV-infected cells. Next, a drug called Vorinostat targets dormant T-cells, giving the patients a strong boost in their poor immune system. The successful trial patients identity is still unknown, but he shared that he is thrilled about the outcome. “It would be great if a cure has happened. My last blood test was a couple of weeks ago and there is no detectable virus,” the man said. While this is a major step in the right direction, there is still a lot of work that needs to be done. “We will continue with medical tests for the next five years and at the moment we are not recommending stopping Art [antiretroviral therapy] but in the future, depending on the test results we may explore this,” Fidler shared.